Nepal were all-out for 50; Bangladesh reached the target with 74 balls to spare.
Bangladesh continued on their good form in the SA Games women's cricket as they clinched their second comfortable win after beating Nepal by 10 wickets.
Bangladesh skipper Salma Khatun won the toss at Pokhara and put Nepal to bat first.
The hosts were out of sorts facing the Bangladeshi bowlers, who were on top from the very beginning.
Only three Nepalese batsmen could reach double-digit scores as they were bundled up for only 50 runs in 19.2 overs.
For Bangladesh Rabeya Khan was the pick of the bowlers as she scalped four wickets for eight runs. Jahanara Alam took 2/2
In reply, Bangladesh openers started well. Both Murshida Khatun and Ayesha Rahman remained unbeaten as Bangladesh claimed an easy win over the hosts.
Murshida scored 23*, while Ayesha was notout on 26. Bangladesh reached the target in 7.4 overs.
Bangladesh will play their last round-robin match against the Maldives, on December 5.